Crank (2006)

Chev Chelios is a professional assassin working for the West Coast crime syndicate. Chev's girlfriend Eve doesn't know what Chev does and Chev is planning to quit the crime syndicate so he can spend more time with her. But for Chev, things about to get very bad, when he learns he has been injected with a poison called "The Beijing Cocktail" by his rival Verona, which will kill him if his heart rate drops. Trying to stay alive and seeking help from friend, Kaylo and Doc Miles, to keep his heart pumping. Chev sets out to find answers as well as protecting Eve, and get his revenge on those who have betrayed him before the poison kills him. [imdb]